Use the electric kazoo in place of your electric guitar.
Send the electric kazoo to a channel on your mixing board.
The electric kazoo operates at microphone or instrument level. Many internal and external sound cards have a built in preamp that can bring the electric kazoo up to line level.
Some sound cards operate at a fixed line level meant for the output of CD, and DVD players. You can use a preamp to bring the electric kazoo up to line level on it's way to your soundcard.